Pharmacokinetics and Tissue Residues of Tylosin in Broiler Chickens
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چکیده
منابع مشابه
Pharmacokinetics of levamisole in broiler breeder chickens.
The pharmacokinetics of levamisole was studied in 20 broiler breeder chickens (chickens that give eggs to breed broilers). A single dose of levamisole (40 mg/kg) was administered orally or intravenously to chickens before the onset of egg production, prelay (age = 22 weeks), and repeated at the peak of egg production (age = 32 weeks). A high-pressure liquid chromatographic with ultraviolet dete...
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To examine the tissue distribution and residues after withdrawal of various beta-agonists (i.e., clenbuterol, salbutamol, and terbutaline) 160 1-d-old broiler chickens were assigned to four groups. During treatment (16 to 35 d), the birds were fed a control diet or a diet containing 1 ppm of clenbuterol, 10 ppm of salbutamol, or 10 ppm of terbutaline. After d 35 all groups received the control ...
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Disposition pharmacokinetic of tylosin concomitantly administrered with either diclazuril (Clinacox ) (1 ® mg/kg feed) and halofuginone (Stenorol ) (3 mg/kg feed) were studied following a single IV, oral and IM ® administrations in broiler chickens. Following IV injection, tylosin serum concentration was best to be 1⁄2 á described by a 2-compartment open model. Diclazuril resulted in a short di...
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The efficacy of tylosin phosphate for the treatment of necrotic enteritis (NE) was investigated in a floor pen study of 2,000 broiler chickens. A model in which Clostridium perfringens was administered in the feed on Days 14 to 16 was used to initiate an outbreak of NE. Treatments, allocated at the pen level in a randomized complete block design, consisted of five levels of tylosin phosphate (0...
متن کاملEvaluation of bioequivalence of two tylosin formulations after oral administration in broiler chickens
Tylosin, a drug mainly used in veterinary medicine, belongs to the macrolide group of antibiotics. In this study the bioequivalence and differences in pharmacokinetics of solution and powdered tylosin formulations were established. The following recommended by EMEA parameters: Cmax, Tmax, AUC were determined. All the investigations were carried out in the populations of 74 broilers chickens. Th...
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ژورنال
عنوان ژورنال: Pharmacology & Pharmacy
سال: 2016
ISSN: 2157-9423,2157-9431
DOI: 10.4236/pp.2016.71006